Alpha-methylacyl-CoA racemase

alpha-methylacyl-CoA racemase
Identifiers
EC number 5.1.99.4
CAS number 156681-44-6
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, an alpha-methylacyl-CoA racemase (EC 5.1.99.4) is an enzyme that catalyzes the chemical reaction

(2S)-2-methylacyl-CoA \rightleftharpoons (2R)-2-methylacyl-CoA

Hence, this enzyme has one substrate, (2S)-2-methylacyl-CoA, and one product, (2R)-2-methylacyl-CoA.

This enzyme belongs to the family of isomerases, to be specific those racemases and epimerases acting on other compounds. The systematic name of this enzyme class is 2-methylacyl-CoA 2-epimerase.

Structural studies

As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes 1X74, 2G04, 2GCE, 2GCI, 2GD0, 2GD2, and 2GD6.

References